Behandlung von Opioidsucht - Eine Übersicht
Behandlung von Opioidsucht - Eine Übersicht
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The following information describes dosages that are commonly used or recommended. However, Beryllium sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.
The initial methadone dose should be carefully titrated to the individual. Too rapid titration for the patient's sensitivity is more likely to produce adverse effects.
There are conflicting reports on whether SIDS occurs with an increased incidence in infants born to women treated with methadone during pregnancy.
Methadone-maintained patients beginning treatment with these antiretroviral drugs should Beryllium monitored for evidence of withdrawal effects and methadone dose should Beryllium adjusted accordingly.
Some heartbeat problems have happened rein people using smaller doses of methadone hydrochloride tablets for treatment of narcotic drug addiction.
Although antiretroviral drugs such as efavirenz, nelfinavir, nevirapine, ritonavir, lopinavir + ritonavir combination are known to inhibit CYPs, they are shown to reduce the plasma levels of methadone, possibly due to their CYP induction activity. Therefore, drugs administered concomitantly with methadone should Beryllium evaluated for interaction potential; clinicians are advised to evaluate individual response to drug therapy.
How to tell if the drug is working: You should have decreased pain, or your withdrawal symptoms should go away.
Patients should Beryllium cautioned that alcohol and other CNS depressants may produce an additive CNS depression when taken with this product and should be avoided.
Do not drive, operate heavy machinery, or do other possible dangerous activities until you know how methadone hydrochloride tablets affect you. Methadone hydrochloride tablets can make you sleepy. Ask your doctor when it is okay to do these activities.
Wenn es durch den Opioidmissbrauch bereits zu einem sehr starken Sauerstoffmangel in dem Körper des Methadontabletten zur Schmerzbehandlung Patienten gekommen sein sollte, können aus diesem Beleg die Pupillen selbst bereits sehr plakativ erweitert sein, da es dann schon zu einer Opioid-Vergiftung gekommen ist.
Rein these patients, even usual therapeutic doses of methadone may decrease respiratory drive while simultaneously increasing airway resistance to the point of apnea. Alternative, non-opioid analgesics should be considered, and methadone should be used at the lowest effective dose and only under careful medical supervision.
Methadone treatment for analgesic therapy rein patients with acute or chronic pain should only be initiated if the potential analgesic or palliative care benefit of treatment with methadone is considered and outweighs the risks.
Methadone has been detected rein amniotic fluid and cord plasma at concentrations proportional to maternal plasma and hinein newborn urine at lower concentrations than corresponding maternal urine.
Methadone undergoes hepatic Nitrogenium-demethylation by cytochrome P-450 isoforms, principally CYP3A4, CYP2B6, CYP2C19, and to a lesser extent by CYP2C9 and CYP2D6. Coadministration of methadone with inducers of these enzymes may result rein more rapid methadone metabolism, and potentially, decreased effects of methadone. Conversely, administration with CYP inhibitors may reduce metabolism and potentiate methadone's effects. Pharmacokinetics of methadone may Beryllium unpredictable when coadministered with drugs that are known to both induce and inhibit CYP enzymes.